Epidermal growth factor (EGF), fractalkine/CX3CL1, IL-1-receptor antagonist (RA), IL-8/CXCL8, interferon inducible protein (IP)-10/CXCL10 were found elevated along with VEGF in 94%–100% of samples [64]. This evidence concerns the gene CX3CL1 and rheumatoid arthritis.