TGFB1 and atherosclerosis: Because EC responses to TGF-β could be important for various processes such as angiogenesis, atherosclerosis, or even for any disorders involving fibrosis due to endothelial to mesenchymal transition, our data with exaggerated response of Cav-2 KO ECs to TGF-β may imply that Cav- 2 plays a role in some of the above mentioned disorders.