Differently from normal tissue, lung tumors have two distinct but interdependent compartments: the parenchyma (neoplastic cells) and the stroma that the neoplastic cells induce and in which they are dispersed, that is why while analyzing control and NSCLC groups we used total number (in tumor islets and stroma) of Foxp3+CD4+, CD4+ and CD8+ T cells. This evidence concerns the gene FOXP3 and neoplasm.