In 2012 Zhang et al. [46] identified and pre-validated seven mRNA transcripts [BRAF (v-raf murine sarcoma viral oncogene homolog B1), CCNI (cyclin I) EGFR, FGF19 (fibroblast growth factor 19), FRS2 (fibroblast growth factor receptor substrate 2), GREB1 (growth regulation by estrogen in breast cancer 1), and LZTS1 (leucine zipper, putative tumor suppressor 1)] expressed in the saliva from patients with NSCLC. This evidence concerns the gene BRCA1 and non-small cell lung carcinoma.