PDE6B and infection: Both wt Mtb and MtbΔRD1::RD1-infected DC displayed a strong apoptotic phenotype as shown by the enhanced percentage of both early (Annexin-V+/FvDye−) and late apoptotic cells (Annexin-V+/FvDye+); in contrast, the infection with Mtb lacking RD1 locus did not promote apoptosis in the infected DC (Fig. 7).