Data set analysis revealed that DC infection with either wild type (wt) Mtb or MtbΔRD1::RD1 (recombinant strain carrying the extended RD1 locus as the parental Mtb) up-regulated the transcription of 215 genes in DC, whereas infection with MtbΔRD1::B412 (recombinant strain deleted in the RD1 region) up-regulated ~100 genes. Here, PDE6B is linked to infection.