Another example of exosomal-mediated immune modulation was described in a study involving TS/A murine mammary tumor-derived exosomes, which were found to act as immune system suppressors to promote tumor progression by inhibiting the differentiation of myeloid precursors in the bone marrow into dendritic cells, partially through induction of IL-6 mRNA [129]. The gene discussed is IL6; the disease is breast cancer.