Some of these mutations are linked to familial autosomal dominant (PARK 1/4: alpha-synuclein, PARK 8: LRRK2) or recessive (PARK 2: Parkin, PARK 6: DJ-1 and PARK 7: PINK1, PARK 13: ATP13A2) forms of PD 10,13,14. This evidence concerns the gene LRRK2 and Parkinson disease.