To our knowledge, we were the first to report a relationship between GLUT-1 expression and radioresistance and revealed that inhibition of GLUT-1 expression by antisense oligodeoxynucleotides (AS-ODN) may improve the radiosensitivity of laryngeal carcinoma, in vitro and in vivo[1]. This evidence concerns the gene SLC2A1 and laryngeal carcinoma.