These experiments demonstrated that BTN2A1 and IGSF8 are targeted for degradation since their protein levels were downregulated during HCMV infection (Fig 5D and 5F, middle panels), whereas the levels of the GFP which was expressed from the same transcript was elevated (Fig 5D and 5F, lower panels). This evidence concerns the gene BTN2A1 and cytomegalovirus infection.