In VSC adipose tissue, the mRNA expression of the VEGF-A angiogenic factor was decreased by 45% (p<0.05) compared to control mice, whereas the mRNA level of the TSP-1 antiangiogenic factor was increased by 41% in ALS-treated mice compared to control mice (p<0.05; Fig 6A). The gene discussed is VEGFA; the disease is amyotrophic lateral sclerosis.