PDGFRB and cancer: Cancer neo-angiogenesis is a multifactorial process and is driven additionally by potential oncogenes like platelet-derived growth factor receptor (PDGFR) and/or fibroblast growth factor receptor (FGFR) signaling as reported in pediatric brain tumors such as medulloblastoma [9] and gliomas [9,10] and rhabdomyosarcoma [11,12], respectively.