As presented in Table 2, tumor size (P < 0.001), pT-stage (P < 0.001), pN-stage (P < 0.001), metastasis (P < 0.001), Fuhrman grade (P < 0.001), microvascular invasion (P = 0.004), necrosis (P < 0.001), sarcomatoid (P < 0.001), ECOG-PS (Eastern Cooperative Oncology Group performance status) (P = 0.001) and SLC1A5 (P < 0.001) were all have a significant impact on OS. The gene discussed is SLC1A5; the disease is neoplasm.