Tie2-expressing monocytes (TEMs) have been found in various human tumors, to form tumor blood vessels and express several proangiogenic factors such as basic fibroblast growth factor (b-FGF), vascular endothelial growth factor (VEGF), and matrix metalloproteinase-9 (MMP-9) [3–5]. The gene discussed is FGF2; the disease is neoplasm.