Of these 6 genes, LPAR1, PSD3, and GNAS are associated with brain-related phenotypes (alcoholism, memory, and brain waves), and LPAR1, PSD3, GNAS, and SRPK2 with eQTLs annotated in GTex or PheGenI in any human tissue (brain regions are not well represented in GTEx). The gene discussed is SRPK2; the disease is alcohol dependence.