The mRNA levels of CCND2 (0.374 ± 0.433 vs. 0.733 ± 0.583, p = 0.012, student’s t test) and CDKN2B (0.143 ± 0.048 vs. 1.172 ± 0.740, p < 0.001, student’s t test), but not RASSF1A (1.635 ± 0.433 vs. 2.150 ± 1.630, p = 0.229, student’s t test) and DLC1 (1.269 ± 0.502 vs. 1.985 ± 1.099, p = 0.085, student’s t test), were significantly lower in the OCSPCs from ascites than those from bulk tumor tissues. Here, CDKN2B is linked to neoplasm.