Among these probe sets/genes, 299 probe sets encoding 240 genes were found to overlap with the NFE2L2-mediated genes (Supplementary Table S3), which is statistically significant (P = 2.2 × 10−14 by hypergeometric cumulative distribution function) and, thus, suggests that NFE2L2-mediated genes are significantly enriched among the lung cancer-related genes. This evidence concerns the gene NFE2L2 and lung cancer.