PCA3 and prostate carcinoma: The highly amplified PCA3-3STA activity was restricted to PCa cell lines (22Rv1, LAPC4, PC-3 and DU145) but remained inactive in benign prostate cell lines (PZ-HPV7 and WPMY-1) and non-prostate carcinoma cell lines such as SW780 (bladder), MGHU3 (bladder) and HepG2 (hepatic) (Figure 1B and 2C).