However, this association did not remain statistically significant after adjusting for diabetes duration, HbA1c, diastolic BP and the presence of other DKD-associated polymorphisms located in three different genes, namely AGER-429T/C and 2184A/G, LTA 252A/G, and NOS3 774C/T and E298D. This evidence concerns the gene AGER and diabetic kidney disease.