Further, overexpression of miR-200, particularly miR-200b and miR-200c, markedly attenuated TGF-β1-induced expression of FN and α-SMA in MRC-5 cell line and in lung fibroblasts isolated from mice with experimental pulmonary fibrosis (Yang et al., 2012). The gene discussed is FN1; the disease is pulmonary fibrosis.