ADAMTS5 and Duchenne muscular dystrophy: Interestingly, many of these proteins are associated with known pathophysiological features of DMD including muscle function (MB, TNNI2, TNNI3), metabolic dysregulation (PGAM1, LDHB, TPI1, FABP3), calcium metabolism (CAMK2A, CAMK2B, CAMK2C, CAPN1), and extracellular matrix remodelling/fibrogenesis (ADAMTS5, THBS4)24.