PDLIM7 and neoplasm: For example, Jansson et al.’s report41 that a single base substitution (G-44T) within the CRE element of the LMP-1 promoter of EBV from the P3HR1 cell line, an African origin tumor-derived BL cell line, altered factor-binding properties of LMP-1 promoter sequence (LRS) and reduced activation of the LMP-1 promoter as compared the corresponding B95-8 sites provides support for this reasoning.