These bivariate correlations further revealed a greater effect in the third trimester of pregnancy, where state and trait anxiety in combination accounted for 14% of variance in HSD11B2 expression levels (R2 = 0.08 and 0.06 respectively), in comparison to 7% (R2 = 0.01 and 0.06 respectively) in Trimester 1 (see Table 1). Here, HSD11B2 is linked to Anxiety.