Additionally, the mutational frequency was >10% in 8 other TSGs in colorectal cancer: FAT4 (19%), TOPORS (15%), PPP2CB (13%), RASL11A (13%), PCDH9 (12%), PRDM2 (12%), LIFR (11%) and TGFBR2 (11%). Here, TGFBR2 is linked to colorectal cancer.