IL18 and type 1 diabetes mellitus: Association of interleukins including IL-18 (interleukin) and IL-12 with T1DM revealed that the −137C/G polymorphism of IL-18 had significant association with T1DM (P = 0.037, P = 0.0001) while no significant relation was observed between −607A/C variant of this gene and T1DM [24, 28].