MUC16 and ovarian carcinoma: The best-studied and longest-utilized biochemical marker of epithelial ovarian cancer is CA125 (Cohen et al., 2014), an antigenic determinant on a high-molecular-weight glycoprotein found on the epithelial surface of reproductive tract organs and the peritoneum and recognized by the murine monoclonal antibody, OC-125 (Yin & Lloyd, 2001).