HDAC9 is also pro-angiogenic [22], and we recently reported that it is required for murine pancreatic cancer cells derived from the KRC (oncogenic Kras combined with loss of RB) genetically engineered mouse model to stimulate proliferation of SV40-transformed murine endothelial cells (SVEC4-10; [13]). Here, RB1 is linked to pancreatic neoplasm.