GNRH1 and ovarian hyperstimulation syndrome: In fact, in women with an extreme response to stimulation a GnRH agonist trigger will be followed by a "freeze-all" strategy to eliminate OHSS risk, while in patients with a low-moderate OHSS risk the GnRH-agonist trigger followed by intensive luteal phase support could allow fresh transfer with good, albeit inferior, reproductive outcome and a significantly reduced risk of OHSS.