KLRK1 and leukemia: For example, leukemia/lymphoma T- and B-cells under a thermal and oxidative stress release exosomes enriched in Natural Killer Group 2, member D (NKG2D) ligands, which abrogate NKG2D-mediated NK-cell cytotoxicity and, thus, may contribute to the immune evasion of leukemia/lymphoma cells [42].