In the locomotion task, the conditional Rac1 knockout and control groups spent comparable time in the central and peripheral areas of the arena (Figure 2G, two-way ANOVA, F(1,28) = 1.055, p = 0.313) and their total distance traveled in the open field has no difference (Figure 2H, t-test, p = 0.24), suggesting that amygdala-specific deletion of Rac1 does not change innate anxiety or motor activity. The gene discussed is RAC1; the disease is Anxiety.