LncRNA TUC339, found in extracellular vesicles derived from hepatocellular carcinoma cells (HCC), has been implicated in tumor growth, adhesion and cell cycle progression [87, 88]. Linc-ROR, another lncRNA enriched in extracellular vesicles from HCC, protects cancer cells from chemotherapy-induced apoptosis and cytotoxicity [89], and MALAT1, an lncRNA enriched in extracellular vesicles from cervical carcinoma and breast cancer cells [86], was associated with tumor metastasis and invasion [90, 91]. The gene discussed is MALAT1; the disease is cancer.