In a prospective apolipoprotein-related mortality risk (AMORIS) study [13], the researchers reported that the apoB100/apoAI ratio was strongly related to increased coronary risk, and was superior to any of the HDL-C related ratios in predicting CHD in a large sample of 69,030 men and 57,168 women above 40 years of age. This evidence concerns the gene APOA1 and coronary artery disorder.