GPNMB and metabolic dysfunction-associated steatohepatitis: Serum GPNMB levels were prominently elevated in SS compared with NGT and T2D, and they were further elevated in NASH compared with SS (20.61 ± 9.00 v.s. 16.34 ± 9.53 ng/ml, p = 0.032) (Fig. 6b).