Rather stable numbers of leukocyte common antigen CD45-positive cells (Supplemental Table S5) suggested a possible changes in the leukocyte population; however, more intensive analysis of the changes in the entire immune system including F4/80-positive hepatic macrophages is necessary to clarify the detailed association between ER stress integration and chronic inflammation during the development of hepatic steatosis. The gene discussed is PTPRC; the disease is Hepatic steatosis.