The expression of serglycin was found to be relatively low in colon cancer cell lines and surprisingly was higher in low aggressive CACO-2 cells as compared to more aggressive HT-29 (mutant BRAF600V→T) and DLD-1 (mutant KRAS13G→D) colon cancer cells [20, 21] (Figure 1(a)). Here, SRGN is linked to malignant colon neoplasm.