Since X-ALD disease pathology is caused by derangements in the metabolism of VLCFA resulting from deletion/mutations of ABCD1, we measured the levels of VLCFA in different cell types (Neurons, OLs and Ast) derived from AMN IPSC, cALD IPSC and control IPSC (Fig 7A and 7B). The gene discussed is ABCD1; the disease is X-linked adrenoleukodystrophy.