EZH2 and breast cancer: Nonetheless, as EZH2 can also modulate DNA methylation (see below), it would be interesting to monitor the existence of direct correlation between EZH2 expression and the expression of these and other miRNAs reported to be epigenetically silenced by methylation in BC, such as miR-498, miR-494, miR-192, miR-183, and miR-134 [126].