All DNA fragmentation assay results directly correlated with the clonal cell populations displaying high levels of effector caspase activity, and helped confirm that optimal antiviral group I intron mediated DENV CA-ΔN Bax or CHIKV NS1-ΔN Bax splice formation and subsequent protein expression leads to full induction of apoptosis in the presence of arbovirus infection. The gene discussed is BAX; the disease is arbovirus infection.