To gain insight into the effect of miR-181a overexpression on REH cell maturation, we stained cells for differentiation markers and found an increase in CD10-negative, CD20-positive, surface IgM-positive, κ-chain-positive, and λ-chain-positive cell populations in 181A1-LV-transduced cells compared with infection control cells (Fig 5A and S1 Fig). This evidence concerns the gene MME and infection.