Similarly, an increased GPI expression was associated with a higher metastatic potential in human lung carcinoma.39 In addition, a recent study showed that GPI/AMF levels were significantly increased in the serum and in neoplastic tissue of patients with endometrial carcinoma.40 In this scenario, to address the significance of GPI/AMF in ccRCC prognosis, we stratified the patients’ population according to protein expression levels. This evidence concerns the gene GPI and lung carcinoma.