EGFR and pancreatic neoplasm: In an in vivo experiment, after the EGFR-targeted MRI of human pancreatic cancer orthotopically implanted into the pancreas of nude mice, it was shown that the ScFvEGFR-IO nanoparticles selectively accumulated within the pancreatic tumors in T2-weighted fast spin echo imaging, as evidenced by a decrease in the MRI signal in the area of the tumor.