However, the tumor infiltration [CD45+ NK cells (green signals), Figure 6D] and cytokine release [24 h PP (high sMICA), Figure 5D] of same PP-inhibited NK cells were strongly reduced in 24 h-incubated samples in absence of cetuximab and consequently non-coated HNSCC tumor spheroids. The gene discussed is PTPRC; the disease is neoplasm.