Interestingly, wildtype (WT) forms of TDP-43, FUS, optineurin, and SOD1 may be recruited into ubiquitinated protein inclusions in sporadic ALS patients (Neumann et al., 2006; Deng et al., 2010; Blokhuis et al., 2013). The gene discussed is FUS; the disease is amyotrophic lateral sclerosis.