The study by Geyer et al. [26], which included women with HER2+, locally advanced or metastatic BC that had progressed after trastuzumab-based therapy, who were randomly assigned to receive lapatinib plus capecitabine or capecitabine alone, did not report results on OS (Geyer et al. [26]), but an updated efficacy analysis showed that the OS was 15.6 months in patients receiving lapatinib plus capecitabine and 15.3 months in the capecitabine alone group (p = 0.177) (Cameron et al. [3]); while time to progression was of 8.4 months and 4.1 months, respectively (p < 0.001). Here, ERBB2 is linked to breast cancer.