CD8A and neoplasm: XRT alone also increased CD8+ cells (mean of CD8 expression percentage of XRT to control group = 38.6%, SD = 9.2%, P = .02, n = 4) (Figure 5A) and decreased PD1+ cells in the tumor (mean of CD8/PD1 expression percentage of XRT to control group = 29.6%, SD = 7.9%, P = .04, n = 4) (Figure 5B); however, and in contrast to MRX34, XRT led to an increase of macrophages and Tregs (Figure 5, C and D).