The miR-34–induced repression of PDL1 was further confirmed by flow cytometry (mean of PDL1 expression percentage of control group = 42.9%, SD = 8.1%; mean of PDL1 expression percentage of MRX34 = 30.4%, SD = 3.8%, P = .04, n = 2) (Figure 4D) and immunohistochemical staining of 344SQ tumor tissue (Figure 4E). The gene discussed is CD274; the disease is neoplasm.