In an earlier study, investigating the ML-1 cell line (another poorly differentiated follicular thyroid cancer cell line) for 24 and 48 h on the 3D clinostat we measured an increase in the production of several extracellular matrix proteins (collagen I and III, laminin, fibronectin, chondroitin sulfate) compared with controls6. The gene discussed is FN1; the disease is thyroid gland follicular carcinoma.