L. Han et al. in their paper “The Renal Protective Effect of Jiangya Tongluo Formula, through Regulation of Adrenomedullin and Angiotensin II, in Rats with Hypertensive Nephrosclerosis” make a conclusion that Jiangya Tongluo Formula can prevent nephrosclerosis through regulation of adrenomedullin and angiotensin II. This evidence concerns the gene ADM and nephrosclerosis.