BCL2 and nonpapillary renal cell carcinoma: Importantly, amongst the genes whose expression directly correlates with the volume of transcription read-through on the upstream gene, we detected the anti-apoptotic oncogene BCL2. This finding unveils a new source of aberrant expression of cancer-related genes and provides a plausible mechanistic basis for the upregulation of BCL2 frequently observed in ccRCC.