For example, extremely broad (>9 kb in length) H3K4me3 peaks were found at KCNC3, encoding a voltage-gated potassium channel linked to spinocerebellar ataxia, a neurodegenerative condition,50 and at the site of multiple neurodevelopmental risk genes including NMDA glutamate receptor subunit GRIN2B and transcription factor SATB2 (refs 51, 52, 53) (Figure 2d). Here, KCNC3 is linked to cerebellar ataxia.