To unravel the discrepancy in the severity of anti-cancer effects observed between HCC cells treated with c-Myc siRNA or JQ1 (Figure 4E and 4F), we performed RNA-Seq analysis in HCCLM3 cells treated with or without 0.5 μM JQ1 for 4 h. The gene discussed is MYC; the disease is hepatocellular carcinoma.