CYP19A1 and endometrial cancer: To address the question of whether the same CYP19A1 variant(s) are associated with E2 levels and endometrial cancer with compatible effect sizes and directions, we used genotype information for 2937 single nucleotide polymorphisms (SNPs) across a 1.2 Mb region encompassing CYP19A1 in 6608 endometrial cancer cases and 37 925 controls of European ancestry, 1733 of whom (all controls) were post-menopausal and had measured E2 and T concentrations.